Annette Birkin

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First appearance: Resident Evil 2

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The wife of William Birkin, the number one researcher of the G-Virus. Always helping from the shadows with her husband's important research, Annette was originally a researcher at Arklay Labs herself, and met William when he was the senior researcher there. After marrying, she gave birth to their daughter, Sherry, two years before he discovered the G-Virus. Even after becoming a mother, she threw herself back into the research out of love for her husband.


Then, after William received permission from Umbrella to begin his new G-Virus Project, she also was allowed to participate in it. Her role was to be in charge of communications with outside parties from their new underground laboratory in Raccoon City. In this way, she became acquainted with Brian Irons, chief the Raccoon City Police Department. Because the members of the S.T.A.R.S. team had learned of the G-Virus Project after the Mansion Incident, William bribed the chief. Through Annette, he was able to monitor police activities.


When Claire Redfield and Leon S. Kennedy sneaked into the research lab, Annette mistook them for spies who were after the G-virus, and openly displayed her hostility toward them. This was because Umbrella had already tried to steal their research, and Annette had come to view everyone with paranoid and suspicious eyes. Since the Umbrella Special Engineering Corps had been sent out in force, William injected himself with the G-virus to protect it from being taken. In doing so, he lost his identity.


When her beloved husband was eaten up by the G-Virus and turned into a monster, an evolution that no one had predicted took place. Annette's remaining responsibility was to retrieve the sample of G-Virus hidden in Sherry's locket and continue her husband's unfinished research.


However, while Annette was wandering about, looking for the locket in her half-mad state, she was fatally attacked by the monster that was once her husband. The image of her own daughter, hovering between life and death, came to her mind. Just before she died, she recovered her senses and led the way to where Sherry lay consumed by the G-Virus. Annette taught Claire how to make a vaccine for it. Then, after speaking of her regrets as a mother and leaving her sincere words of apology to her daughter, Annette left this world.